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Power and Predictive Accuracy of Polygenic Risk Scores
Polygenic scores have recently been used to summarise genetic effects among an ensemble of markers that do not individually achieve significance in a large-scale association study. Markers are selected using an initial training sample and used to construct a score in an independent replication sampl...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605113/ https://www.ncbi.nlm.nih.gov/pubmed/23555274 http://dx.doi.org/10.1371/journal.pgen.1003348 |