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Complement activation fragment C5a receptors, CD88 and C5L2, are associated with neurofibrillary pathology

BACKGROUND: Alzheimer’s disease (AD) is a neurodegenerative dementia characterized by the decline of cognition and the presence of neuropathological changes including neuronal loss, neurofibrillary pathology and extracellular senile plaques. A neuroinflammatory process is also triggered and compleme...

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Detalles Bibliográficos
Autores principales: Fonseca, Maria I, McGuire, Susan O, Counts, Scott E, Tenner, Andrea J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605123/
https://www.ncbi.nlm.nih.gov/pubmed/23394121
http://dx.doi.org/10.1186/1742-2094-10-25