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Complement activation fragment C5a receptors, CD88 and C5L2, are associated with neurofibrillary pathology
BACKGROUND: Alzheimer’s disease (AD) is a neurodegenerative dementia characterized by the decline of cognition and the presence of neuropathological changes including neuronal loss, neurofibrillary pathology and extracellular senile plaques. A neuroinflammatory process is also triggered and compleme...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605123/ https://www.ncbi.nlm.nih.gov/pubmed/23394121 http://dx.doi.org/10.1186/1742-2094-10-25 |