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Synthesis, characterization and in vitro studies of doxorubicin-loaded magnetic nanoparticles grafted to smart copolymers on A549 lung cancer cell line

BACKGROUND: The aim of present study was to develop the novel methods for chemical and physical modification of superparamagnetic iron oxide nanoparticles (SPIONs) with polymers via covalent bonding entrapment. These modified SPIONs were used for encapsulation of anticancer drug doxorubicin. METHOD:...

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Detalles Bibliográficos
Autores principales: Akbarzadeh, Abolfazl, Samiei, Mohammad, Joo, Sang Woo, Anzaby, Maryam, Hanifehpour, Younes, Nasrabadi, Hamid Tayefi, Davaran, Soodabeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605180/
https://www.ncbi.nlm.nih.gov/pubmed/23244711
http://dx.doi.org/10.1186/1477-3155-10-46