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Dimeric RNA Recognition Regulates HIV-1 Genome Packaging

How retroviruses regulate the amount of RNA genome packaged into each virion has remained a long-standing question. Our previous study showed that most HIV-1 particles contain two copies of viral RNA, indicating that the number of genomes packaged is tightly regulated. In this report, we examine the...

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Detalles Bibliográficos
Autores principales: Nikolaitchik, Olga A., Dilley, Kari A., Fu, William, Gorelick, Robert J., Tai, S.-H. Sheldon, Soheilian, Ferri, Ptak, Roger G., Nagashima, Kunio, Pathak, Vinay K., Hu, Wei-Shau
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605237/
https://www.ncbi.nlm.nih.gov/pubmed/23555259
http://dx.doi.org/10.1371/journal.ppat.1003249