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The Enterovirus 71 A-particle Forms a Gateway to Allow Genome Release: A CryoEM Study of Picornavirus Uncoating

Since its discovery in 1969, enterovirus 71 (EV71) has emerged as a serious worldwide health threat. This human pathogen of the picornavirus family causes hand, foot, and mouth disease, and also has the capacity to invade the central nervous system to cause severe disease and death. Upon binding to...

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Detalles Bibliográficos
Autores principales: Shingler, Kristin L., Yoder, Jennifer L., Carnegie, Michael S., Ashley, Robert E., Makhov, Alexander M., Conway, James F., Hafenstein, Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605244/
https://www.ncbi.nlm.nih.gov/pubmed/23555253
http://dx.doi.org/10.1371/journal.ppat.1003240