PPARβ/δ Regulates Glucocorticoid- and Sepsis-Induced FOXO1 Activation and Muscle Wasting

FOXO1 is involved in glucocorticoid- and sepsis-induced muscle wasting, in part reflecting regulation of atrogin-1 and MuRF1. Mechanisms influencing FOXO1 expression in muscle wasting are poorly understood. We hypothesized that the transcription factor peroxisome proliferator-activated receptor β/δ...

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Detalles Bibliográficos
Autores principales: Castillero, Estibaliz, Alamdari, Nima, Aversa, Zaira, Gurav, Aniket, Hasselgren, Per-Olof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605288/
https://www.ncbi.nlm.nih.gov/pubmed/23555761
http://dx.doi.org/10.1371/journal.pone.0059726

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605288/
https://www.ncbi.nlm.nih.gov/pubmed/23555761
http://dx.doi.org/10.1371/journal.pone.0059726

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