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Plasminogen Controls Inflammation and Pathogenesis of Influenza Virus Infections via Fibrinolysis
Detrimental inflammation of the lungs is a hallmark of severe influenza virus infections. Endothelial cells are the source of cytokine amplification, although mechanisms underlying this process are unknown. Here, using combined pharmacological and gene-deletion approaches, we show that plasminogen c...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605290/ https://www.ncbi.nlm.nih.gov/pubmed/23555246 http://dx.doi.org/10.1371/journal.ppat.1003229 |