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The Conserved SKN-1/Nrf2 Stress Response Pathway Regulates Synaptic Function in Caenorhabditis elegans

The Nrf family of transcription factors plays a critical role in mediating adaptive responses to cellular stress and defends against neurodegeneration, aging, and cancer. Here, we report a novel role for the Caenorhabditis elegans Nrf homolog SKN-1 in regulating synaptic transmission at neuromuscula...

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Detalles Bibliográficos
Autores principales: Staab, Trisha A., Griffen, Trevor C., Corcoran, Connor, Evgrafov, Oleg, Knowles, James A., Sieburth, Derek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605294/
https://www.ncbi.nlm.nih.gov/pubmed/23555279
http://dx.doi.org/10.1371/journal.pgen.1003354