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A comparison of medetomidine and its active enantiomer dexmedetomidine when administered with ketamine in mice

BACKGROUND: Medetomidine-ketamine (MK) and dexmedetomidine-ketamine (DK) are widely used to provide general anaesthesia in laboratory animals, but have not been compared directly in many of these species, including rodents. This study aimed to compare the onset and depth of anaesthesia, and changes...

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Detalles Bibliográficos
Autores principales: Burnside, Wesley M, Flecknell, Paul A, Cameron, Angus I, Thomas, Aurélie A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605306/
https://www.ncbi.nlm.nih.gov/pubmed/23497612
http://dx.doi.org/10.1186/1746-6148-9-48