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In-Cell Protease Assay Systems Based on Trans-Localizing Molecular Beacon Proteins Using HCV Protease as a Model System

This study describes a sensitive in-cell protease detection system that enables direct fluorescence detection of a target protease and its inhibition inside living cells. This live-cell imaging system provides a fluorescent molecular beacon protein comprised of an intracellular translocation signal...

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Detalles Bibliográficos
Autores principales: Kim, Jeong Hee, Lee, Min Jun, Hwang, Inhwan, Hwang, Hyun Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605327/
https://www.ncbi.nlm.nih.gov/pubmed/23555756
http://dx.doi.org/10.1371/journal.pone.0059710