Cargando…

Characterisation of ATP-Dependent Mur Ligases Involved in the Biogenesis of Cell Wall Peptidoglycan in Mycobacterium tuberculosis

ATP-dependent Mur ligases (Mur synthetases) play essential roles in the biosynthesis of cell wall peptidoglycan (PG) as they catalyze the ligation of key amino acid residues to the stem peptide at the expense of ATP hydrolysis, thus representing potential targets for antibacterial drug discovery. In...

Descripción completa

Detalles Bibliográficos
Autores principales: Munshi, Tulika, Gupta, Antima, Evangelopoulos, Dimitrios, Guzman, Juan David, Gibbons, Simon, Keep, Nicholas H., Bhakta, Sanjib
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605390/
https://www.ncbi.nlm.nih.gov/pubmed/23555903
http://dx.doi.org/10.1371/journal.pone.0060143