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Characterisation of ATP-Dependent Mur Ligases Involved in the Biogenesis of Cell Wall Peptidoglycan in Mycobacterium tuberculosis
ATP-dependent Mur ligases (Mur synthetases) play essential roles in the biosynthesis of cell wall peptidoglycan (PG) as they catalyze the ligation of key amino acid residues to the stem peptide at the expense of ATP hydrolysis, thus representing potential targets for antibacterial drug discovery. In...
Autores principales: | Munshi, Tulika, Gupta, Antima, Evangelopoulos, Dimitrios, Guzman, Juan David, Gibbons, Simon, Keep, Nicholas H., Bhakta, Sanjib |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605390/ https://www.ncbi.nlm.nih.gov/pubmed/23555903 http://dx.doi.org/10.1371/journal.pone.0060143 |
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