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Reduced expression of DACT2 promotes hepatocellular carcinoma progression: involvement of methylation-mediated gene silencing

BACKGROUND: Hepatocellular carcinoma (HCC) is one of the most aggressive malignancies in humans, and its prognosis is generally poor even after surgery. Many advances have been made to understand the pathogenesis of HCC; however, the molecular mechanisms that lead to hepatocarcinogenesis and progres...

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Detalles Bibliográficos
Autores principales: Gao, Sheng, Yang, Zhe, Zheng, Zhi-Yun, Yao, Jia, Zhang, Feng, Wu, Li-Ming, Xie, Hai-Yang, zhou, Lin, Zheng, Shu-Sen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605395/
https://www.ncbi.nlm.nih.gov/pubmed/23496880
http://dx.doi.org/10.1186/1477-7819-11-57