IL-17A and IFN-γ Synergistically Induce RNase 7 Expression via STAT3 in Primary Keratinocytes

Human keratinocytes produce several antimicrobial peptides and proteins (AMP) which contribute to the protection of human skin against infection. RNase 7 is a major AMP involved in cutaneous defense with a high expression in keratinocytes and a broad spectrum of antimicrobial activity. The cytokine...

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Detalles Bibliográficos
Autores principales: Simanski, Maren, Rademacher, Franziska, Schröder, Lena, Schumacher, Hanna Maria, Gläser, Regine, Harder, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605401/
https://www.ncbi.nlm.nih.gov/pubmed/23555696
http://dx.doi.org/10.1371/journal.pone.0059531

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605401/
https://www.ncbi.nlm.nih.gov/pubmed/23555696
http://dx.doi.org/10.1371/journal.pone.0059531

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