Multiple Roles of the Extracellular Vestibule Amino Acid Residues in the Function of the Rat P2X4 Receptor

The binding of ATP to trimeric P2X receptors (P2XR) causes an enlargement of the receptor extracellular vestibule, leading to opening of the cation-selective transmembrane pore, but specific roles of vestibule amino acid residues in receptor activation have not been evaluated systematically. In this...

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Detalles Bibliográficos
Autores principales: Rokic, Milos B., Stojilkovic, Stanko S., Vavra, Vojtech, Kuzyk, Pavlo, Tvrdonova, Vendula, Zemkova, Hana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605439/
https://www.ncbi.nlm.nih.gov/pubmed/23555667
http://dx.doi.org/10.1371/journal.pone.0059411

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605439/
https://www.ncbi.nlm.nih.gov/pubmed/23555667
http://dx.doi.org/10.1371/journal.pone.0059411

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