Intratumour Diversity of Chromosome Copy Numbers in Neuroblastoma Mediated by On-Going Chromosome Loss from a Polyploid State

Neuroblastomas (NBs) are tumours of the sympathetic nervous system accounting for 8–10% of paediatric cancers. NBs exhibit extensive intertumour genetic heterogeneity, but their extent of intratumour genetic diversity has remained unexplored. We aimed to assess intratumour genetic variation in NBs w...

Descripción completa

Detalles Bibliográficos
Autores principales: Lundberg, Gisela, Jin, Yuesheng, Sehic, Daniel, Øra, Ingrid, Versteeg, Rogier, Gisselsson, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605453/
https://www.ncbi.nlm.nih.gov/pubmed/23555645
http://dx.doi.org/10.1371/journal.pone.0059268

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605453/
https://www.ncbi.nlm.nih.gov/pubmed/23555645
http://dx.doi.org/10.1371/journal.pone.0059268

Ejemplares similares