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Intratumour Diversity of Chromosome Copy Numbers in Neuroblastoma Mediated by On-Going Chromosome Loss from a Polyploid State

Neuroblastomas (NBs) are tumours of the sympathetic nervous system accounting for 8–10% of paediatric cancers. NBs exhibit extensive intertumour genetic heterogeneity, but their extent of intratumour genetic diversity has remained unexplored. We aimed to assess intratumour genetic variation in NBs w...

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Detalles Bibliográficos
Autores principales:	Lundberg, Gisela, Jin, Yuesheng, Sehic, Daniel, Øra, Ingrid, Versteeg, Rogier, Gisselsson, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605453/ https://www.ncbi.nlm.nih.gov/pubmed/23555645 http://dx.doi.org/10.1371/journal.pone.0059268

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