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Intracellular Gating in an Inward-facing State of Aspartate Transporter Glt(Ph) Is Regulated by the Movements of the Helical Hairpin HP2
Sodium-coupled neurotransmitter transporters play a key role in neuronal signaling by clearing excess transmitter from the synapse. Structural data on a trimeric archaeal aspartate transporter, Glt(Ph), have provided valuable insights into structural features of human excitatory amino acid transport...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605641/ https://www.ncbi.nlm.nih.gov/pubmed/23386619 http://dx.doi.org/10.1074/jbc.M112.438432 |