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Intracellular Gating in an Inward-facing State of Aspartate Transporter Glt(Ph) Is Regulated by the Movements of the Helical Hairpin HP2

Sodium-coupled neurotransmitter transporters play a key role in neuronal signaling by clearing excess transmitter from the synapse. Structural data on a trimeric archaeal aspartate transporter, Glt(Ph), have provided valuable insights into structural features of human excitatory amino acid transport...

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Detalles Bibliográficos
Autores principales:	Zomot, Elia, Bahar, Ivet
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2013
Materias:	Computational Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605641/ https://www.ncbi.nlm.nih.gov/pubmed/23386619 http://dx.doi.org/10.1074/jbc.M112.438432

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