TRPM2 links oxidative stress to the NLRP3 inflammasome activation

Exposure to particulate crystals can induce oxidative stress in phagocytes, which triggers NLRP3 inflammasome-mediated interleukin 1β (IL-1β) secretion to initiate undesirable inflammatory responses that are associated with both autoinflammatory and metabolic diseases. Although mitochondrial reactiv...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhong, Zhenyu, Zhai, Yougang, Liang, Shuang, Mori, Yasuo, Han, Renzhi, Sutterwala, Fayyaz S, Qiao, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605705/
https://www.ncbi.nlm.nih.gov/pubmed/23511475
http://dx.doi.org/10.1038/ncomms2608

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605705/
https://www.ncbi.nlm.nih.gov/pubmed/23511475
http://dx.doi.org/10.1038/ncomms2608

Ejemplares similares