Recombination-restarted replication makes inverted chromosome fusions at inverted repeats

Impediments to DNA replication are known to induce gross chromosomal rearrangements (GCR) and copy number variations (CNV). GCRs/CNVs underlie human genomic disorders(1) and are a feature of cancer(2). During cancer development environmental factors and oncogene-driven proliferation promote replicat...

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Detalles Bibliográficos
Autores principales: Mizuno, Ken’Ichi, Miyabe, Izumi, Schalbetter, Stephanie, Carr, Antony M., Murray, Johanne M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605775/
https://www.ncbi.nlm.nih.gov/pubmed/23178809
http://dx.doi.org/10.1038/nature11676

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605775/
https://www.ncbi.nlm.nih.gov/pubmed/23178809
http://dx.doi.org/10.1038/nature11676

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