Cargando…
Recombination-restarted replication makes inverted chromosome fusions at inverted repeats
Impediments to DNA replication are known to induce gross chromosomal rearrangements (GCR) and copy number variations (CNV). GCRs/CNVs underlie human genomic disorders(1) and are a feature of cancer(2). During cancer development environmental factors and oncogene-driven proliferation promote replicat...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2012
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605775/ https://www.ncbi.nlm.nih.gov/pubmed/23178809 http://dx.doi.org/10.1038/nature11676 |