Cargando…

Central Synapses Release a Resource-Efficient Amount of Glutamate

Why synapses release a certain amount of neurotransmitter is poorly understood. Here we combine patch-clamp electrophysiology with computer simulations to estimate how much glutamate is discharged at two distinct central synapses of the rat. We find that, regardless of some uncertainty over synaptic...

Descripción completa

Detalles Bibliográficos
Autores principales: Savtchenko, Leonid P., Sylantyev, Sergiy, Rusakov, Dmitri A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605778/
https://www.ncbi.nlm.nih.gov/pubmed/23242311
http://dx.doi.org/10.1038/nn.3285