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Structural insights into lipid-dependent reversible dimerization of human GLTP

Human glycolipid transfer protein (hsGLTP) forms the prototypical GLTP fold and is characterized by a broad transfer selectivity for glycosphingolipids (GSLs). The GLTP mutation D48V near the ‘portal entrance’ of the glycolipid binding site has recently been shown to enhance selectivity for sulfatid...

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Detalles Bibliográficos
Autores principales: Samygina, Valeria R., Ochoa-Lizarralde, Borja, Popov, Alexander N., Cabo-Bilbao, Aintzane, Goni-de-Cerio, Felipe, Molotkovsky, Julian G., Patel, Dinshaw J., Brown, Rhoderick E., Malinina, Lucy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606038/
https://www.ncbi.nlm.nih.gov/pubmed/23519669
http://dx.doi.org/10.1107/S0907444913000024