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The Drosophila melanogaster CHD1 Chromatin Remodeling Factor Modulates Global Chromosome Structure and Counteracts HP1a and H3K9me2

CHD1 is a conserved chromatin remodeling factor that localizes to active genes and functions in nucleosome assembly and positioning as well as histone turnover. Mouse CHD1 is required for the maintenance of stem cell pluripotency while human CHD1 may function as a tumor suppressor. To investigate th...

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Detalles Bibliográficos
Autores principales: Bugga, Lakshmi, McDaniel, Ivy E., Engie, Liana, Armstrong, Jennifer A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606111/
https://www.ncbi.nlm.nih.gov/pubmed/23533627
http://dx.doi.org/10.1371/journal.pone.0059496