pSTAT3: a target biomarker to study the pharmacology of the anti-IL-21R antibody ATR-107 in human whole blood

BACKGROUND: IL-21 has been shown to play an important role in autoimmune diseases. ATR-107 is an antibody which directly targets the IL-21 receptor (IL-21R). To aid the clinical development of ATR-107, there is a need for understanding the mechanism of action (MOA) of this antibody when assessing ta...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Ming, Pleasic-Williams, Susan, Lin, Tsung H, Wunderlich, David A, Cheng, John B, Masferrer, Jaime L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606126/
https://www.ncbi.nlm.nih.gov/pubmed/23496892
http://dx.doi.org/10.1186/1479-5876-11-65

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606126/
https://www.ncbi.nlm.nih.gov/pubmed/23496892
http://dx.doi.org/10.1186/1479-5876-11-65

Ejemplares similares