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Systemic release of high mobility group box 1 (HMGB1) protein is associated with severe and fatal Plasmodium falciparum malaria

BACKGROUND: Severe falciparum malaria (SM) pathogenesis has been attributed, in part, to deleterious systemic host inflammatory responses to infection. High mobility group box 1 (HMGB1) protein is an important mediator of inflammation implicated in sepsis pathophysiology. METHODS: Plasma levels of H...

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Detalles Bibliográficos
Autores principales: Higgins, Sarah J, Xing, Katharine, Kim, Hani, Kain, Dylan C, Wang, Feng, Dhabangi, Aggrey, Musoke, Charles, Cserti-Gazdewich, Christine M, Tracey, Kevin J, Kain, Kevin C, Liles, W Conrad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606128/
https://www.ncbi.nlm.nih.gov/pubmed/23506269
http://dx.doi.org/10.1186/1475-2875-12-105