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Characterization of Protective Immune Responses Induced by Pneumococcal Surface Protein A in Fusion with Pneumolysin Derivatives

Pneumococcal surface protein A (PspA) and Pneumolysin derivatives (Pds) are important vaccine candidates, which can confer protection in different models of pneumococcal infection. Furthermore, the combination of these two proteins was able to increase protection against pneumococcal sepsis in mice....

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Detalles Bibliográficos
Autores principales: Goulart, Cibelly, da Silva, Thais Raquel, Rodriguez, Dunia, Politano, Walter Rodrigo, Leite, Luciana C. C., Darrieux, Michelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606166/
https://www.ncbi.nlm.nih.gov/pubmed/23533636
http://dx.doi.org/10.1371/journal.pone.0059605