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Fv1 Restriction and Retrovirus Vaccine Immunity in Apobec3-Deficient 129P2 Mice

Understanding the host genetics of the immune response in retrovirus infection models could provide insights for basic HIV vaccine discovery. In Friend retrovirus (FV) infection of mice, Fv1 differentially inhibits N-tropic versus B-tropic FV infection by mediating a capsid-dependent post-entry bloc...

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Detalles Bibliográficos
Autores principales: Halemano, Kalani, Barrett, Bradley S., Li, Sam X., Harper, Michael S., Smith, Diana S., Heilman, Karl J., Santiago, Mario L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606284/
https://www.ncbi.nlm.nih.gov/pubmed/23533681
http://dx.doi.org/10.1371/journal.pone.0060500