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Intramyocardial Transplantation and Tracking of Human Mesenchymal Stem Cells in a Novel Intra-Uterine Pre-Immune Fetal Sheep Myocardial Infarction Model: A Proof of Concept Study

Although stem-cell therapies have been suggested for cardiac-regeneration after myocardial-infarction (MI), key-questions regarding the in-vivo cell-fate remain unknown. While most available animal-models require immunosuppressive-therapy when applying human cells, the fetal-sheep being pre-immune u...

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Detalles Bibliográficos
Autores principales: Emmert, Maximilian Y., Weber, Benedikt, Wolint, Petra, Frauenfelder, Thomas, Zeisberger, Steffen M., Behr, Luc, Sammut, Sebastien, Scherman, Jacques, Brokopp, Chad E., Schwartländer, Ruth, Vogel, Viola, Vogt, Peter, Grünenfelder, Jürg, Alkadhi, Hatem, Falk, Volkmar, Boss, Andreas, Hoerstrup, Simon P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606388/
https://www.ncbi.nlm.nih.gov/pubmed/23533575
http://dx.doi.org/10.1371/journal.pone.0057759