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Intramyocardial Transplantation and Tracking of Human Mesenchymal Stem Cells in a Novel Intra-Uterine Pre-Immune Fetal Sheep Myocardial Infarction Model: A Proof of Concept Study
Although stem-cell therapies have been suggested for cardiac-regeneration after myocardial-infarction (MI), key-questions regarding the in-vivo cell-fate remain unknown. While most available animal-models require immunosuppressive-therapy when applying human cells, the fetal-sheep being pre-immune u...
Autores principales: | Emmert, Maximilian Y., Weber, Benedikt, Wolint, Petra, Frauenfelder, Thomas, Zeisberger, Steffen M., Behr, Luc, Sammut, Sebastien, Scherman, Jacques, Brokopp, Chad E., Schwartländer, Ruth, Vogel, Viola, Vogt, Peter, Grünenfelder, Jürg, Alkadhi, Hatem, Falk, Volkmar, Boss, Andreas, Hoerstrup, Simon P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606388/ https://www.ncbi.nlm.nih.gov/pubmed/23533575 http://dx.doi.org/10.1371/journal.pone.0057759 |
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