Expression of Fibroblast Growth Factor-21 in Muscle Is Associated with Lipodystrophy, Insulin Resistance and Lipid Disturbances in Patients with HIV

BACKGROUND: Fibroblast growth factor (FGF)-21 is a novel regulator of glucose and lipid metabolism. Recently, increased FGF-21 mRNA expression in muscle was found in patients with type 2 diabetes, but the role for FGF-21 in muscle is not well understood. Patients with HIV-infection and lipodystrophy...

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Detalles Bibliográficos
Autores principales: Lindegaard, Birgitte, Hvid, Thine, Grøndahl, Thomas, Frosig, Christian, Gerstoft, Jan, Hojman, Pernille, Pedersen, Bente Klarlund
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606412/
https://www.ncbi.nlm.nih.gov/pubmed/23533568
http://dx.doi.org/10.1371/journal.pone.0055632