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Evaluating Purifying Selection in the Mitochondrial DNA of Various Mammalian Species
Mitochondrial DNA (mtDNA), the circular DNA molecule inside the mitochondria of all eukaryotic cells, has been shown to be under the effect of purifying selection in several species. Traditional testing of purifying selection has been based simply on ratios of nonsynonymous to synonymous mutations,...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606437/ https://www.ncbi.nlm.nih.gov/pubmed/23533597 http://dx.doi.org/10.1371/journal.pone.0058993 |