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Evaluating Purifying Selection in the Mitochondrial DNA of Various Mammalian Species

Mitochondrial DNA (mtDNA), the circular DNA molecule inside the mitochondria of all eukaryotic cells, has been shown to be under the effect of purifying selection in several species. Traditional testing of purifying selection has been based simply on ratios of nonsynonymous to synonymous mutations,...

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Detalles Bibliográficos
Autores principales:	Soares, Pedro, Abrantes, Diogo, Rito, Teresa, Thomson, Noel, Radivojac, Predrag, Li, Biao, Macaulay, Vincent, Samuels, David C., Pereira, Luísa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606437/ https://www.ncbi.nlm.nih.gov/pubmed/23533597 http://dx.doi.org/10.1371/journal.pone.0058993

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