αB-crystallin stimulates VEGF secretion and tumor cell migration and correlates with enhanced distant metastasis in head and neck squamous cell carcinoma

BACKGROUND: αB-crystallin is able to modulate vascular endothelial growth factor (VEGF) secretion. In many solid tumors VEGF is associated with angiogenesis, metastasis formation and poor prognosis. We set out to assess whether αB-crystallin expression is correlated with worse prognosis and whether...

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Detalles Bibliográficos
Autores principales: van de Schootbrugge, Chantal, Bussink, Johan, Span, Paul N, Sweep, Fred CGJ, Grénman, Reidar, Stegeman, Hanneke, Pruijn, Ger JM, Kaanders, Johannes HAM, Boelens, Wilbert C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606599/
https://www.ncbi.nlm.nih.gov/pubmed/23506259
http://dx.doi.org/10.1186/1471-2407-13-128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606599/
https://www.ncbi.nlm.nih.gov/pubmed/23506259
http://dx.doi.org/10.1186/1471-2407-13-128

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