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Nanog-dependent function of Tet1 and Tet2 in establishment of pluripotency

Molecular control of the pluripotent state is thought to reside in a core circuitry of master transcription factors including the homeodomain-containing protein Nanog(1–2), which plays an essential role in establishing ground state pluripotency during somatic cell reprogramming(3–4). While the genom...

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Detalles Bibliográficos
Autores principales: Costa, Yael, Ding, Junjun, Theunissen, Thorold W., Faiola, Francesco, Hore, Timothy A., Shliaha, Pavel V., Fidalgo, Miguel, Saunders, Arven, Lawrence, Moyra, Dietmann, Sabine, Das, Satyabrata, Levasseur, Dana N., Li, Zhe, Xu, Mingjiang, Reik, Wolf, Silva, José C.R., Wang, Jianlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606645/
https://www.ncbi.nlm.nih.gov/pubmed/23395962
http://dx.doi.org/10.1038/nature11925