Tregs are Dysfunctional in Vivo in a Spontaneous Murine Model of Crohn’s Disease

Although regulatory T cells (Tregs) have been implicated in inflammatory bowel disease (IBD), Tregs from Crohn’s disease (CD) patients are increased in number and function normally in vitro. To clarify this disparity, we studied Treg function in vivo using a spontaneous model of CD-like ileitis. We...

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Detalles Bibliográficos
Autores principales: Ishikawa, Dai, Okazawa, Akira, Corridoni, Daniele, Jia, Li Guo, Wang, Ziao Ming, Xin, Wei, Arseneau, Kristen O., Pizarro, Theresa T., Cominelli, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606708/
https://www.ncbi.nlm.nih.gov/pubmed/22785225
http://dx.doi.org/10.1038/mi.2012.67

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606708/
https://www.ncbi.nlm.nih.gov/pubmed/22785225
http://dx.doi.org/10.1038/mi.2012.67

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