Tumor Inhibition by DepoVax-Based Cancer Vaccine Is Accompanied by Reduced Regulatory/Suppressor Cell Proliferation and Tumor Infiltration

A successful cancer vaccine needs to overcome the effects of immune-suppressor cells such as Treg lymphocytes, suppressive cytokine-secreting Tr1 cells, and myeloid-derived suppressor cells (MDSCs), while enhancing tumor-specific immune responses. Given the relative poor efficacy associated with cur...

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Detalles Bibliográficos
Autores principales: Karkada, Mohan, Quinton, Tara, Blackman, Rachelle, Mansour, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606802/
https://www.ncbi.nlm.nih.gov/pubmed/23533812
http://dx.doi.org/10.1155/2013/753427

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606802/
https://www.ncbi.nlm.nih.gov/pubmed/23533812
http://dx.doi.org/10.1155/2013/753427

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