Integrated Pharmacometrics and Systems Pharmacology Model-Based Analyses to Guide GnRH Receptor Modulator Development for Management of Endometriosis

Endometriosis is a gynecological condition resulting from proliferation of endometrial-like tissue outside the endometrial cavity. Estrogen suppression therapies, mediated through gonadotropin-releasing hormone (GnRH) modulation, decrease endometriotic implants and diminish associated pain albeit at...

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Detalles Bibliográficos
Autores principales: Riggs, M M, Bennetts, M, van der Graaf, P H, Martin, S W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606940/
https://www.ncbi.nlm.nih.gov/pubmed/23887363
http://dx.doi.org/10.1038/psp.2012.10

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606940/
https://www.ncbi.nlm.nih.gov/pubmed/23887363
http://dx.doi.org/10.1038/psp.2012.10

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