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An improved mouse model that rapidly develops fibrosis in non-alcoholic steatohepatitis

Non-alcoholic steatohepatitis (NASH) is a progressive fibrotic disease, the pathogenesis of which has not been fully elucidated. One of the most common models used in NASH research is a nutritional model where NASH is induced by feeding a diet deficient in both methionine and choline. However, the d...

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Detalles Bibliográficos
Autores principales: Matsumoto, Masahiko, Hada, Natsuko, Sakamaki, Yoshiyuki, Uno, Akiko, Shiga, Toshihiko, Tanaka, Chiaki, Ito, Tsuneo, Katsume, Asao, Sudoh, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607137/
https://www.ncbi.nlm.nih.gov/pubmed/23305254
http://dx.doi.org/10.1111/iep.12008