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Galantamine potentiates the neuroprotective effect of memantine against NMDA-induced excitotoxicity

The combination of memantine, an N-methyl-d-aspartate (NMDA) receptor antagonist, with an acetylcholinesterase inhibitor (AChEI) is the current standard of care in Alzheimer's disease (AD). Galantamine, an AChEI currently marketed for the treatment of AD, exerts memory-enhancing and neuroprotec...

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Detalles Bibliográficos
Autores principales: Lopes, João P, Tarozzo, Glauco, Reggiani, Angelo, Piomelli, Daniele, Cavalli, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607148/
https://www.ncbi.nlm.nih.gov/pubmed/23532860
http://dx.doi.org/10.1002/brb3.118