Gene therapy with AAV2-CDNF provides functional benefits in a rat model of Parkinson's disease

Cerebral dopamine neurotrophic factor (CDNF) protein has been shown to protect the nigrostriatal dopaminergic pathway when given as intrastriatal infusions in rat and mouse models of Parkinson's disease (PD). In this study, we assessed the neuroprotective effect of CDNF delivered with a recombi...

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Detalles Bibliográficos
Autores principales: Bäck, Susanne, Peränen, Johan, Galli, Emilia, Pulkkila, Päivi, Lonka-Nevalaita, Liina, Tamminen, Tuulia, Voutilainen, Merja H, Raasmaja, Atso, Saarma, Mart, Männistö, Pekka T, Tuominen, Raimo K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607149/
https://www.ncbi.nlm.nih.gov/pubmed/23532969
http://dx.doi.org/10.1002/brb3.117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607149/
https://www.ncbi.nlm.nih.gov/pubmed/23532969
http://dx.doi.org/10.1002/brb3.117

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