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Gene therapy with AAV2-CDNF provides functional benefits in a rat model of Parkinson's disease
Cerebral dopamine neurotrophic factor (CDNF) protein has been shown to protect the nigrostriatal dopaminergic pathway when given as intrastriatal infusions in rat and mouse models of Parkinson's disease (PD). In this study, we assessed the neuroprotective effect of CDNF delivered with a recombi...
Autores principales: | Bäck, Susanne, Peränen, Johan, Galli, Emilia, Pulkkila, Päivi, Lonka-Nevalaita, Liina, Tamminen, Tuulia, Voutilainen, Merja H, Raasmaja, Atso, Saarma, Mart, Männistö, Pekka T, Tuominen, Raimo K |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607149/ https://www.ncbi.nlm.nih.gov/pubmed/23532969 http://dx.doi.org/10.1002/brb3.117 |
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