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A library of programmable DNAzymes that operate in a cellular environment

DNAzymes were used as inhibitory agents in a variety of experimental disease settings, such as cancer, viral infections and even HIV. Drugs that become active only upon the presence of preprogrammed abnormal environmental conditions may enable selective molecular therapy by targeting abnormal cells...

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Detalles Bibliográficos
Autores principales: Kahan-Hanum, Maya, Douek, Yehonatan, Adar, Rivka, Shapiro, Ehud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607177/
https://www.ncbi.nlm.nih.gov/pubmed/23525068
http://dx.doi.org/10.1038/srep01535