Cargando…

Cellular Strategies for Regulating Functional and Nonfunctional Protein Aggregation

Growing evidence suggests that aggregation-prone proteins are both harmful and functional for a cell. How do cellular systems balance the detrimental and beneficial effect of protein aggregation? We reveal that aggregation-prone proteins are subject to differential transcriptional, translational, an...

Descripción completa

Detalles Bibliográficos
Autores principales: Gsponer, Jörg, Babu, M. Madan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607227/
https://www.ncbi.nlm.nih.gov/pubmed/23168257
http://dx.doi.org/10.1016/j.celrep.2012.09.036