PML(NLS(-)) Inhibits Cell Apoptosis and Promotes Proliferation in HL-60 Cells

Promyelocytic leukemia (PML) is a cell-growth suppressor, and PML-retinoic acid receptor α (PML-RARα) is known as a fusion gene of acute promyelocytic leukemia (APL). Studies have reported that neutrophil elastase(NE) cleaved bcr-1-derived PML-RARα in early myeloid cells leading to the removal of nu...

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Detalles Bibliográficos
Autores principales: Gao, Yuan-Mei, Zhong, Liang, Zhang, Xi, Hu, Xiu-Xiu, Liu, Bei-Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607234/
https://www.ncbi.nlm.nih.gov/pubmed/23532460
http://dx.doi.org/10.7150/ijms.5560

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607234/
https://www.ncbi.nlm.nih.gov/pubmed/23532460
http://dx.doi.org/10.7150/ijms.5560

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