A novel submicron emulsion system loaded with vincristine–oleic acid ion-pair complex with improved anticancer effect: in vitro and in vivo studies

BACKGROUND: Vincristine (VCR), which is a widely used antineoplastic drug, was integrated with a submicron-emulsion drug-delivery system to enhance the anticancer effect. METHODS: After the formation of a VCR-oleic acid ion-pair complex (VCR-OA), the VCR-OA-loaded submicron emulsion (VCR-OA-SME), pr...

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Detalles Bibliográficos
Autores principales: Zhang, Ting, Zheng, Yong, Peng, Qiang, Cao, Xi, Gong, Tao, Zhang, Zhirong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607420/
https://www.ncbi.nlm.nih.gov/pubmed/23658485
http://dx.doi.org/10.2147/IJN.S41775

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607420/
https://www.ncbi.nlm.nih.gov/pubmed/23658485
http://dx.doi.org/10.2147/IJN.S41775

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