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A novel submicron emulsion system loaded with vincristine–oleic acid ion-pair complex with improved anticancer effect: in vitro and in vivo studies

BACKGROUND: Vincristine (VCR), which is a widely used antineoplastic drug, was integrated with a submicron-emulsion drug-delivery system to enhance the anticancer effect. METHODS: After the formation of a VCR-oleic acid ion-pair complex (VCR-OA), the VCR-OA-loaded submicron emulsion (VCR-OA-SME), pr...

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Detalles Bibliográficos
Autores principales:	Zhang, Ting, Zheng, Yong, Peng, Qiang, Cao, Xi, Gong, Tao, Zhang, Zhirong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2013
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607420/ https://www.ncbi.nlm.nih.gov/pubmed/23658485 http://dx.doi.org/10.2147/IJN.S41775

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