Loss of Mfn2 results in progressive, retrograde degeneration of dopaminergic neurons in the nigrostriatal circuit

Mitochondria continually undergo fusion and fission, and these dynamic processes play a major role in regulating mitochondrial function. Studies of several genes associated with familial Parkinson's disease (PD) have implicated aberrant mitochondrial dynamics in the disease pathology, but the i...

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Detalles Bibliográficos
Autores principales: Pham, Anh H., Meng, Shuxia, Chu, Quynh N., Chan, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607482/
https://www.ncbi.nlm.nih.gov/pubmed/22859504
http://dx.doi.org/10.1093/hmg/dds311

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607482/
https://www.ncbi.nlm.nih.gov/pubmed/22859504
http://dx.doi.org/10.1093/hmg/dds311

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