TGF-Beta Suppresses VEGFA-Mediated Angiogenesis in Colon Cancer Metastasis

The FET cell line, derived from an early stage colon carcinoma, is non-tumorigenic in athymic nude mice. Engineered FET cells that express TGF-α (FETα) display constitutively active EGFR/ErbB signaling. These cells readily formed xenograft tumors in athymic nude mice. Importantly, FETα cells retaine...

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Detalles Bibliográficos
Autores principales: Geng, Liying, Chaudhuri, Anathbandhu, Talmon, Geoffrey, Wisecarver, James L., Wang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607554/
https://www.ncbi.nlm.nih.gov/pubmed/23536895
http://dx.doi.org/10.1371/journal.pone.0059918

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607554/
https://www.ncbi.nlm.nih.gov/pubmed/23536895
http://dx.doi.org/10.1371/journal.pone.0059918

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